Sanders Marcus, Grundmann Oliver
Department of Medicinal Chemistry, University of Florida, FL, USA. .
Altern Med Rev. 2011 Sep;16(3):228-38.
Osteoarthritis is one of the most common chronic inflammatory conditions seen in the general population. Current pharmacological treatments focus on reduction of pain and increased mobility to improve overall quality of life. However, the relief afforded by current standard care is often insufficient and can be associated with significant side effects. Many patients, therefore, seek the option of non-standard therapies, such as nutritional and herbal supplements, acupuncture, and exercise regimens. Glucosamine, Harpagophytum procumbens, and acupuncture are among the most commonly used complementary and alternative medicine approaches utilized by patients suffering from osteoarthritis. Their clinical relevance, safety, and potential mechanisms of action are discussed in this review.
骨关节炎是普通人群中最常见的慢性炎症性疾病之一。目前的药物治疗主要集中在减轻疼痛和增加关节活动度以提高整体生活质量。然而，当前标准治疗所提供的缓解往往不足，并且可能伴有显著的副作用。因此，许多患者寻求非标准疗法，如营养补充剂、草药补充剂、针灸和运动方案。氨基葡萄糖、魔鬼爪和针灸是骨关节炎患者最常用的补充和替代医学方法。本文综述了它们的临床相关性、安全性及潜在作用机制。
