Hlatshwayo Sphamandla, Thembane Nokukhanya, Krishna Suresh Babu Naidu, Gqaleni Nceba, Ngcobo Mlungisi
Traditional Medicine Laboratory, University of KwaZulu Natal, Durban 4041, South Africa.
Department of Biomedical Sciences, Mangosuthu University of Technology, Durban 4026, South Africa.
Plants (Basel). 2025 Jan 13;14(2):206. doi: 10.3390/plants14020206.
Medicinal plants are sources of crude traditional herbal medicines that are utilized to reduce the risk of, treat, or manage diseases in most indigenous communities. This is due to their potent antioxidant and anti-inflammatory effects. It is estimated that about 80% of the population in developing countries rely on herbal traditional medicines for healthcare. This signifies the need for traditional herbal medicines, which are polyherbal formulations prepared by traditional health practitioners. This review examines preparatory steps to extract bioactive phytoconstituents and post-extraction processes to increase the potency of the extracted bioactive phytoconstituents. Achieving this will allow for the reduced use of plant materials and promote the sustainable use of the limited resource of medicinal plants, especially in our South African context. Electronic ethnobotanical books and online databases were used to find studies that focus on phytoconstituent extraction and post-extraction processing to enhance the potency of the extracted bioactive phytoconstituents. Modification of the extracted bioactive phytoconstituents to synthesize daughter compounds facilitates an enhancement in their potency and bioavailability. Based on the data collected through this review, the importance of understanding the properties of the targeted phytoconstituents is essential in selecting the required extraction method. This determines the quality and yield of extracted bioactive phytoconstituents.
药用植物是天然传统草药的来源，在大多数土著社区中被用于降低疾病风险、治疗或管理疾病。这归因于它们强大的抗氧化和抗炎作用。据估计，发展中国家约80%的人口依靠草药传统药物进行医疗保健。这表明对传统草药的需求，传统草药是由传统医疗从业者配制的多草药配方。本综述研究了提取生物活性植物成分的制备步骤以及提取后提高提取的生物活性植物成分效力的过程。实现这一点将减少植物材料的使用，并促进对药用植物有限资源的可持续利用，特别是在我们南非的背景下。利用电子民族植物学书籍和在线数据库查找专注于植物成分提取和提取后加工以提高提取的生物活性植物成分效力的研究。对提取的生物活性植物成分进行修饰以合成子化合物有助于提高其效力和生物利用度。基于通过本综述收集的数据，了解目标植物成分的特性对于选择所需的提取方法至关重要。这决定了提取的生物活性植物成分的质量和产量。
