[Clinical manifestations of acquired immunodeficiency syndrome (AIDS), with reference to cases reported in Japan and our observations on two of HIV-infected homosexuals].

This article provides an overview of the clinical presentations of human immunodeficiency virus (HIV) infection, including some of the early and less severe diseases, such as acute HIV infection, persistent generalized lymphadenopathy (PGL) and acquired immunodeficiency syndrome (AIDS) related complex (ARC), and full-blown AIDS. The salient features of 24 cases of AIDS reported in Japan were summarized. There was no difference in clinical features between hemophiliacs (16 cases) and homosexual males (8 cases), except for a preponderance of cases of cytomegalovirus infection in the latter group. The new prognostic staging system, based on physiologic deficits, for AIDS was applicable to Japanese patients with AIDS. In addition, a three-year follow-up study on two of HIV-infected homosexuals was presented.