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[视网膜前膜的免疫组织化学鉴别]

[Immunohistochemical differentiation of periretinal membranes].

作者信息

Meier-Gibbons F, Schaffner T, Körner F

机构信息

Universitäts-Augenklinik und Patholog, Institut der Universität Bern.

出版信息

Klin Monbl Augenheilkd. 1990 May;196(5):372-3. doi: 10.1055/s-2008-1046197.

Abstract

The etiology of periretinal membranes, a complication of various ocular diseases, trauma, and ocular surgery, is still unknown. In the study reported here, 134 surgically removed periretinal membranes were semiquantitatively analyzed by immunohistochemical and morphological method (antigens S 100, GFAP, leukocyte antigens, factor 8; fibrosis). It was found that the cell population of the membranes varied both morphologically and immunohistochemically according to the disease. However, the RPE cell count did not correlate with the number of retinal tears recorded in the patients' histories.

摘要

视网膜前膜是各种眼部疾病、外伤及眼科手术后的一种并发症,其病因尚不清楚。在本文报道的研究中,采用免疫组织化学和形态学方法(抗原S 100、胶质纤维酸性蛋白、白细胞抗原、因子8;纤维化)对134例手术切除的视网膜前膜进行了半定量分析。结果发现,根据疾病不同,这些膜的细胞群落在形态学和免疫组织化学方面均有所差异。然而,视网膜色素上皮(RPE)细胞计数与患者病历中记录的视网膜裂孔数量并无关联。

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