Marshall W F, McLimans C A, Yu P K, Allerberger F J, Van Scoy R E, Anhalt J P
Division of Infectious Diseases and Internal Medicine, Mayo Clinic, Rochester, MN 55905.
Mayo Clin Proc. 1990 Jun;65(6):787-92. doi: 10.1016/s0025-6196(12)62567-1.
Escherichia coli O157:H7 is a recently recognized enteric pathogen that causes acute hemorrhagic colitis. Although the infection is usually self-limited, it may be complicated by hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. At our institution, stool specimens are now routinely cultured for this organism. To determine the prevalence of E. coli O157:H7-associated diarrhea in our patient population, we surveyed all submitted stool cultures for 6 months for this organism. Specimens were screened for non-sorbitol fermenting E. coli and confirmed by slide-agglutination and immobilization testing. Of 2,164 specimens, 10 yielded E. coli O157:H7. It was the fourth most common bacterial stool pathogen found. Bloody diarrhea and abdominal pain were the most common symptoms of the infected patients. E. coli O157:H7 causes sporadic infections in our patient population and should be considered in the differential diagnosis of acute hemorrhagic colitis.
大肠埃希菌O157:H7是一种最近才被认识的肠道病原体，可引起急性出血性结肠炎。虽然感染通常为自限性，但可能并发溶血尿毒综合征和血栓性血小板减少性紫癜。在我们机构，现在常规对粪便标本进行该病原体的培养。为确定我们患者群体中与大肠埃希菌O157:H7相关腹泻的患病率，我们对所有提交的粪便培养物进行了为期6个月的该病原体调查。标本经筛选非山梨醇发酵大肠埃希菌，并通过玻片凝集和制动试验进行确认。在2164份标本中，10份检出大肠埃希菌O157:H7。它是第四常见的细菌性粪便病原体。血性腹泻和腹痛是感染患者最常见的症状。大肠埃希菌O157:H7在我们的患者群体中引起散发性感染，在急性出血性结肠炎的鉴别诊断中应予以考虑。
