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基于互联网的与传统的局部前列腺癌治疗后夫妇性咨询的随机试验。

A randomized trial of internet-based versus traditional sexual counseling for couples after localized prostate cancer treatment.

机构信息

Department of Behavioral Science, University of Texas MD Anderson Cancer Center, Houston, Texas 77230-1439, USA.

出版信息

Cancer. 2012 Jan 15;118(2):500-9. doi: 10.1002/cncr.26308. Epub 2011 Sep 26.

Abstract

BACKGROUND

After treatment for prostate cancer, multidisciplinary sexual rehabilitation involving couples appears more promising than traditional urologic treatment for erectile dysfunction (ED). The authors of this report conducted a randomized trial comparing traditional or internet-based sexual counseling with waitlist (WL) control.

METHODS

Couples were randomized adaptively to a 3-month WL, a 3-session face-to-face format (FF), or an internet-based format (WEB1). A second internet-based group (WEB2) was added to examine the relation between web site use and outcomes. At baseline, post-WL, post-treatment, and 6-month, and 12-month follow-up assessments, participants completed the International Index of Erectile Function (IIEF), the Female Sexual Function Index (FSFI), the Brief Symptom Inventory-18 to measure emotional distress, and the abbreviated Dyadic Adjustment Scale.

RESULTS

Outcomes did not change during the WL period. Of 115 couples that were randomized to FF or WEB1 and 71 couples in the WEB2 group, 34% dropped out. Neither drop-outs nor improvements in outcomes differed significantly between the 3 treatment groups. In a linear mixed-model analysis that included all participants, mean ± standard deviation IIEF scores improved significantly across time (baseline, 29.7 ± 17.9; 12 months, 36.2 ± 22.4; P < .001). FSFI scores also improved significantly (baseline, 15.4 ± 8.5; 12 months, 18.2 ± 10.7; P = .034). Better IIEF scores were associated with finding an effective medical treatment for ED and normal female sexual function at baseline. In the WEB2 group, IIEF scores improved significantly more in men who completed >75% of the intervention.

CONCLUSIONS

An internet-based sexual counseling program for couples was as effective as a brief, traditional sex therapy format in producing enduring improvements in sexual outcomes after prostate cancer.

摘要

背景

在治疗前列腺癌后,多学科性康复治疗(涉及夫妻双方)似乎比传统泌尿科治疗勃起功能障碍(ED)更有前景。本报告的作者进行了一项随机试验,比较了传统或基于互联网的性咨询与候补名单(WL)对照组。

方法

夫妻双方适应性随机分为 3 个月的 WL、3 次面对面形式(FF)或基于互联网的形式(WEB1)。增加了第二个基于互联网的小组(WEB2),以检验网站使用与结果之间的关系。在基线、WL 后、治疗后和 6 个月、12 个月随访评估时,参与者完成了国际勃起功能指数(IIEF)、女性性功能指数(FSFI)、简短症状清单-18 以测量情绪困扰以及简短的对偶调整量表。

结果

在 WL 期间,结果没有变化。在随机分配至 FF 或 WEB1 的 115 对夫妻和 WEB2 组的 71 对夫妻中,有 34%的人退出。3 个治疗组之间的脱落率和结果改善均无显著差异。在包括所有参与者的线性混合模型分析中,IIEF 评分的平均值±标准差显著随时间改善(基线,29.7±17.9;12 个月,36.2±22.4;P<.001)。FSFI 评分也显著改善(基线,15.4±8.5;12 个月,18.2±10.7;P=0.034)。在基线时,IIEF 评分较高与找到有效的 ED 治疗方法和正常的女性性功能有关。在 WEB2 组中,完成>75%干预的男性的 IIEF 评分显著提高。

结论

针对夫妻的基于互联网的性咨询计划与简短的传统性治疗形式一样,在前列腺癌后产生持久的性结果改善方面同样有效。

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