Penchansky L, Krause J R
South Med J. 1979 Apr;72(4):500-1. doi: 10.1097/00007611-197904000-00038.
The bone marrow trephine biopsy has become a common procedure for evaluating hematopoietic abnormalities. Occasionally, the first clue to an infectious process is obtained from this source. A bone marrow biopsy, done to evaluate pancytopenia in a patient who had received a renal transplant, revealed large intranuclear inclusions diagnostic of cytomegalovirus. Antibody titers were initially negative but rose over the next few weeks to confirm the diagnosis. Even though the bone marrow biopsy may not be the best site for finding CMV inclusions, the careful examination of a random bone marrow biopsy, particularly in an immunosuppressed individual, may contribute to the diagnosis.
骨髓环钻活检已成为评估造血异常的常见操作。偶尔，从这个来源可获得感染过程的首个线索。对一名接受肾移植的患者进行骨髓活检以评估全血细胞减少症时，发现了诊断为巨细胞病毒的大核内包涵体。抗体滴度最初为阴性，但在接下来的几周内上升以确诊。尽管骨髓活检可能不是发现巨细胞病毒包涵体的最佳部位，但仔细检查随机的骨髓活检，特别是在免疫抑制个体中，可能有助于诊断。
