Meier-Sydow J
Klinikum der J. W. Goethe-Universität, Frankfurt/Main.
Pneumologie. 1990 Feb;44 Suppl 1:127-30.
Connective tissue diseases are relatively frequently associated with pulmonary manifestations, and should thus always be included in the pneumological differential diagnostic evaluation. The nature and incidence of the various pulmonary forms of manifestation are discussed. Pulmonary accompanying reactions (clinically and radiologically "silent" alveolitis) which, if granulocytic, have proved to represent a negative prognostic factor, must be distinguished from these manifestations. The diagnosis and treatment of the underlying disorder and the pulmonary manifestations are briefly discussed--with respect to treatment, in particular to immunosuppressive or cytostatic agents. It is shown that, today, the diagnostic evaluation generally presents no problems, while treatment often produces unsatisfactory results.
结缔组织病相对频繁地伴有肺部表现，因此在肺病鉴别诊断评估中应始终予以考虑。文中讨论了各种肺部表现形式的性质和发病率。必须将肺部伴随反应（临床和放射学上“无症状”的肺泡炎）与这些表现区分开来，若为粒细胞性肺泡炎，已证明其为不良预后因素。文中简要讨论了基础疾病及肺部表现的诊断和治疗——在治疗方面，尤其涉及免疫抑制剂或细胞毒性药物。结果表明，如今诊断评估一般不存在问题，而治疗往往效果不尽人意。
