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固有曲率:毫米尺度切向皮质-皮质连接的标志物?

Intrinsic curvature: a marker of millimeter-scale tangential cortico-cortical connectivity?

机构信息

Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge, UK.

出版信息

Int J Neural Syst. 2011 Oct;21(5):351-66. doi: 10.1142/S0129065711002948.

DOI:10.1142/S0129065711002948
PMID:21956929
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3446200/
Abstract

In this paper, we draw a link between cortical intrinsic curvature and the distributions of tangential connection lengths. We suggest that differential rates of surface expansion not only lead to intrinsic curvature of the cortical sheet, but also to differential inter-neuronal spacing. We propose that there follows a consequential change in the profile of neuronal connections: specifically an enhancement of the tendency towards proportionately more short connections. Thus, the degree of cortical intrinsic curvature may have implications for short-range connectivity.

摘要

在本文中,我们在皮质固有曲率与切向连接长度分布之间建立了联系。我们认为,表面扩张的差异速率不仅导致皮质片的固有曲率,还导致神经元之间的间隔的差异。我们提出,随后神经元连接的形态发生了相应的变化:具体来说,更倾向于形成比例更多的短连接。因此,皮质固有曲率的程度可能对短程连接具有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/87824d4c9dec/ukmss-48206-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/bd6d4df9e059/ukmss-48206-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/8ba38f6903f3/ukmss-48206-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/1c7067efe49d/ukmss-48206-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/9f6e5c370d05/ukmss-48206-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/87824d4c9dec/ukmss-48206-f0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/bd6d4df9e059/ukmss-48206-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/8ba38f6903f3/ukmss-48206-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/1c7067efe49d/ukmss-48206-f0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/9f6e5c370d05/ukmss-48206-f0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43cc/3446200/87824d4c9dec/ukmss-48206-f0005.jpg

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A METHODOLOGY FOR ANALYZING CURVATURE IN THE DEVELOPING BRAIN FROM PRETERM TO ADULT.一种从早产儿到成人阶段分析发育中大脑曲率的方法。
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