尼日利亚一家三级医疗中心淋巴瘤的十五年回顾
A fifteen-year review of lymphomas in a Nigerian tertiary healthcare centre.
作者信息
Oluwasola A Olayiwola, Olaniyi John A, Otegbayo Jesse A, Ogun Gabriel O, Akingbola Titi S, Ukah Cornelius O, Akang Effiong E U, Aken'Ova Yetunde A
机构信息
Department of Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
出版信息
J Health Popul Nutr. 2011 Aug;29(4):310-6. doi: 10.3329/jhpn.v29i4.8446.
In Africa, epidemiological data on the effect of the HIV epidemic on the occurrence of lymphomas are scanty. The 1990s witnessed the alarming rates of HIV/AIDS in Nigeria. The prevalence of HIV/AIDS in Nigeria increased from 1.8% in 1991 to 4.4% in 2005. The aim of this study was to determine whether there have been any changes in the frequency and pattern of lymphomas in view of the HIV/AIDS epidemic in the country. This is a retrospective study of all lymphoma cases diagnosed during 1991-2005. The prevalence of lymphomas declined from 1.4% to 0.7% of surgical biopsies during 1991-2005. There was a decline in the proportion of high-grade non-Hodgkin lymphoma and Burkitt's lymphoma from 79.1% and 45.8% respectively to 21.1% and 13.6% respectively. There is a suggestion that the HIV/AIDS epidemic in the country may not have influenced the pattern of occurrence of both major histomorphological types of lymphoma in Ibadan.
在非洲，关于艾滋病毒流行对淋巴瘤发病影响的流行病学数据匮乏。20世纪90年代，尼日利亚的艾滋病毒/艾滋病感染率令人震惊。尼日利亚的艾滋病毒/艾滋病患病率从1991年的1.8%上升至2005年的4.4%。本研究旨在确定鉴于该国的艾滋病毒/艾滋病流行情况，淋巴瘤的发病频率和模式是否发生了任何变化。这是一项对1991年至2005年期间诊断的所有淋巴瘤病例的回顾性研究。1991年至2005年期间，淋巴瘤在手术活检中的患病率从1.4%降至0.7%。高级别非霍奇金淋巴瘤和伯基特淋巴瘤的比例分别从79.1%和45.8%降至21.1%和13.6%。有迹象表明，该国的艾滋病毒/艾滋病流行可能并未影响伊巴丹两种主要组织形态学类型淋巴瘤的发病模式。
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