Akinde Olakanmi Ralph, Phillips Adekoyejo Abiodun, Oguntunde Olubanji Ajibola, Afolayan Olatunji Michael
Department of Anatomic and Molecular Pathology, College of Medicine, University of Lagos/Lagos University Teaching Hospital, PMB 12003, Lagos, Nigeria.
Department of Surgery, College of Medicine, University of Lagos/Lagos University Teaching Hospital, PMB 12003, Lagos, Nigeria.
J Cancer Epidemiol. 2015;2015:842032. doi: 10.1155/2015/842032. Epub 2015 Jan 5.
Background. Cancer is a leading cause of death worldwide and about 70% of all cancer deaths occurred in low- and middle-income countries. The cancer mortality pattern is quite different in Africa compared to other parts of the world. Extensive literature research showed little or no information about the overall deaths attributable to cancer in Nigeria. Aims and Objectives. This study aims at providing data on the patterns of cancer deaths in our center using the hospital and autopsy death registers. Methodology. Demographic, clinical data of patients who died of cancer were extracted from death registers in the wards and mortuary over a period of 14 years (2000-2013). Results. A total of 1436 (4.74%) cancer deaths out of 30287 deaths recorded during the period. The male to female ratio was 1 : 2.2 and the peak age of death was between 51 and 60 years. Overall, breast cancer was responsible for most of the deaths. Conclusion. The study shows that the cancers that accounted for majority of death occurred in organs that were accessible to screening procedures and not necessary for survival. We advise regular screening for precancerous lesions in these organs so as to reduce the mortality rate and burden of cancer.
背景。癌症是全球主要死因之一,约70%的癌症死亡发生在低收入和中等收入国家。与世界其他地区相比,非洲的癌症死亡率模式差异很大。广泛的文献研究表明,关于尼日利亚癌症所致总体死亡的信息很少或几乎没有。目的。本研究旨在利用医院和尸检死亡登记册提供我们中心癌症死亡模式的数据。方法。在14年期间(2000 - 2013年),从病房和停尸房的死亡登记册中提取死于癌症患者的人口统计学和临床数据。结果。在此期间记录的30287例死亡中,共有1436例(4.74%)为癌症死亡。男女比例为1∶2.2,死亡高峰年龄在51至60岁之间。总体而言,乳腺癌导致的死亡最多。结论。该研究表明,导致大多数死亡的癌症发生在可进行筛查且并非生存必需的器官。我们建议对这些器官定期筛查癌前病变,以降低癌症死亡率和负担。