University Psychiatric Centre Catholic University Leuven, Kortenberg, Belgium.
Disabil Rehabil. 2012;34(1):1-12. doi: 10.3109/09638288.2011.587090. Epub 2011 Sep 29.
The excess cardiovascular morbidity associated with schizophrenia is attributed to an interplay between behavioural (physical inactivity, unhealthy diet, substance abuse), genetic and illness related factors, as well as the effects of antipsychotic treatment. Patients have limited access to physical healthcare with less opportunity for cardiovascular risk prevention and treatment programmes than the non-psychiatric population. The aim of this paper is to improve physical activity (PA) within rehabilitation programmes for people with schizophrenia.
The development process consisted of: a) systematic literature review on PA in schizophrenia in eight databases up to May 2010; b) review on existing national and international guidelines; c) consensus meetings, and d) formulation of the final consensus document.
There is insufficient evidence for the relative contribution of PA reducing cardio-metabolic risks in people with schizophrenia. Demographical, biological, psychological, cognitive-behavioural, emotional, social and environmental barriers for PA could be identified.
Although PA outcomes on cardio-metabolic parameters are still unknown, the benefits of physical activity as part of a larger lifestyle programme are sufficient for the recommendation that persons with schizophrenia follow the 2008 U.S. Department of Health and Human Services PA Guidelines with specific adaptations based on disease and treatment-related adverse effects.
精神分裂症相关的心血管发病率过高,可归因于行为(体力活动不足、饮食不健康、滥用药物)、遗传和疾病相关因素,以及抗精神病药物治疗的影响。与非精神科患者相比,精神分裂症患者获得身体保健的机会有限,进行心血管风险预防和治疗方案的机会更少。本文旨在改善精神分裂症患者康复计划中的体力活动(PA)。
开发过程包括:a)在截至 2010 年 5 月的 8 个数据库中对精神分裂症中的 PA 进行系统文献回顾;b)对现有的国家和国际指南进行回顾;c)共识会议;以及 d)制定最终的共识文件。
PA 降低精神分裂症患者心血管代谢风险的相对贡献证据不足。可以确定 PA 的人口统计学、生物学、心理学、认知行为、情绪、社会和环境障碍。
尽管 PA 对心血管代谢参数的结果尚不清楚,但将体力活动作为更大的生活方式计划的一部分的益处足以推荐精神分裂症患者遵循 2008 年美国卫生与公众服务部的 PA 指南,并根据疾病和治疗相关的不良反应进行具体调整。