Neuroscience and Ophthalmology Research at Merck 351 Sumneytown Pike, North Wales, Pennsylvania 19454, USA.
Nat Rev Drug Discov. 2011 Sep 30;10(10):715-6. doi: 10.1038/nrd3559.
The challenges of developing drugs for central nervous system disorders have led some major companies to reduce or discontinue investment in the field, even though the unmet medical need is substantial. How can the wealth of basic research knowledge in neuroscience be successfully translated into new therapies?
开发中枢神经系统疾病药物面临的挑战,导致一些大公司减少甚至停止在该领域的投资,尽管这方面的未满足医疗需求巨大。那么,神经科学领域丰富的基础研究知识怎样才能成功转化为新疗法呢?