Yazawa Y, Kitahara M
Department of Otolaryngology, Shiga University of Medical Science, Otsu, Japan.
Ann Otol Rhinol Laryngol. 1990 Jul;99(7 Pt 1):524-8. doi: 10.1177/000348949009900705.
The wide range in incidence rates reported for bilateral Meniere's disease results mainly from the lack of established clinical criteria for bilaterality, and from follow-ups of varying duration. In order to help determine a reasonable bilateral involvement rate, we examined histologic reports of temporal bones with endolymphatic hydrops. We reviewed the literature on temporal bone autopsies from 1938 to 1988, and selected 72 cases for histologic examination. Of the 72 cases, 67 (93%) showed endolymphatic hydrops, 2 (2.8%) showed collapse, and 3 (4.2%) showed membranous labyrinths of normal appearance. Twenty of the 67 endolymphatic hydrops cases (29.9%) displayed bilateral involvement, suggesting a rate of bilaterality in Meniere's disease of approximately 30%.
双侧梅尼埃病报告的发病率范围很广，主要是由于缺乏确定双侧性的既定临床标准，以及随访时间长短不一。为了帮助确定合理的双侧受累率，我们检查了伴有内淋巴积水的颞骨组织学报告。我们回顾了1938年至1988年有关颞骨尸检的文献，并选择了72例进行组织学检查。在这72例中，67例（93%）显示内淋巴积水，2例（2.8%）显示塌陷，3例（4.2%）显示外观正常的膜迷路。67例内淋巴积水病例中有20例（29.9%）表现为双侧受累，提示梅尼埃病的双侧发生率约为30%。
