Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Palo Alto, California 94305, USA.
AJNR Am J Neuroradiol. 2012 Jan;33(1):119-23. doi: 10.3174/ajnr.A2713. Epub 2011 Sep 29.
CH measurements can often be useful in the diagnosis of inner ear malformations associated with SNHL. Our aim was to establish the relationship between CH and age by using analysis of CT images in patients who underwent coronal CT scans of the temporal bone between 2001 and 2007.
We measured CH on coronal CT scans of the temporal bone of 422 ears scanned from 2001 to 2007 in 211 patients, 1 month to 23 years of age. Using multivariate linear regression analysis, we determined the relationship of CH to age, sex, and HL type. In addition, 11 patients with multiple scans at different ages were assessed for change in CH with age.
Average CH was 5.3 mm (normal range, 4.4-6.2 mm). Analysis showed no statistically significant change in CH across ages from 1 month to 23 years (95% CI for regression line slope = -0.003, 0.013). Likewise, there were no statistically significant differences in CH for patients with multiple scans at different ages. ICW increased with age as expected with increased cranial size. A small difference in CH between sexes was noted with males having greater CHs than females (P < .01). All patients with hypoplastic cochleas, defined by a CH <2 SDs from the mean (4.48 mm for males and 4.25 mm for females), had HL with a positive predictive value of 86%.
CH does not change from 1 month of age to adulthood and is slightly greater in males than in females.
CH 测量值通常可用于诊断与 SNHL 相关的内耳畸形。我们的目的是通过分析 2001 年至 2007 年间进行的颞骨冠状 CT 扫描的患者的 CT 图像,来建立 CH 与年龄之间的关系。
我们测量了 211 例年龄在 1 个月至 23 岁之间的患者的 422 只耳朵的颞骨冠状 CT 扫描中的 CH 值。使用多元线性回归分析,我们确定了 CH 与年龄、性别和 HL 类型的关系。此外,还评估了 11 例在不同年龄进行多次扫描的患者 CH 值随年龄的变化。
平均 CH 值为 5.3mm(正常范围为 4.4-6.2mm)。分析表明,从 1 个月到 23 岁,CH 值在各年龄段之间没有统计学上的显著变化(95%CI 回归线斜率=-0.003,0.013)。同样,在不同年龄进行多次扫描的患者之间,CH 值也没有统计学上的显著差异。ICW 随着颅腔大小的增加而增加,这是符合预期的。我们注意到,男性的 CH 值略大于女性,男女之间存在微小的 CH 值差异(P<.01)。所有 CH 值小于平均值 2 个标准差(男性为 4.48mm,女性为 4.25mm)的发育不全耳蜗患者都存在 HL,其阳性预测值为 86%。
CH 从 1 个月到成年期都不会发生变化,且男性的 CH 值略大于女性。