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胆红素的实验室检测

Laboratory measurement of bilirubin.

作者信息

Sykes E, Epstein E

机构信息

Department of Clinical Pathology, William Beaumont Hospital, Royal Oak, Michigan.

出版信息

Clin Perinatol. 1990 Jun;17(2):397-416.

PMID:2196137
Abstract

Several methods for determination of total bilirubin and its fractions have been critically discussed. Methods for serum determinations are summarized in Table 1. Because results of direct bilirubin cannot necessarily be equated with conjugated bilirubin, care must be taken in interpreting results from different laboratories, and clinicians are encouraged to become familiar with methods in use at their own institutions. Despite problems reported in the literature, bilirubin determinations, together with a reference range established for one's own patient population, should provide valuable information for patient management.

摘要

已经对几种测定总胆红素及其组分的方法进行了批判性讨论。血清测定方法总结于表1中。由于直接胆红素的结果不一定等同于结合胆红素,因此在解释不同实验室的结果时必须谨慎,并且鼓励临床医生熟悉其所在机构所使用的方法。尽管文献中报道了一些问题,但胆红素测定以及为自身患者群体建立的参考范围,应为患者管理提供有价值的信息。

相似文献

1
Laboratory measurement of bilirubin.胆红素的实验室检测
Clin Perinatol. 1990 Jun;17(2):397-416.
2
Bilirubin measurements in neonates.
Clin Lab Med. 1981 Jun;1(2):311-27.
3
[Quantitative chromatographic-spectrophotometric determination of unconjugated bilirubin in the urine of newborn infants after phototherapy and in the amniotic fluid in cases of Rhesus incompatible pregnancies].
Wien Klin Wochenschr. 1972 Oct 6;84(40):621-7.
4
Transcutaneous bilirubin measurements in full-term infants.足月儿经皮胆红素测量
Pediatrics. 1982 Sep;70(3):464-7.
5
Interlaboratory bilirubin variability.实验室间胆红素变异性。
Pediatrics. 1982 Mar;69(3):277-81.
6
Evaluation of a point-of-care direct spectrophotometric method for measurement of total serum bilirubin in term and near-term neonates.评估一种用于测量足月儿和近足月儿血清总胆红素的即时检测直接分光光度法。
J Perinatol. 2006 Feb;26(2):100-5. doi: 10.1038/sj.jp.7211436.
7
Neonatal transcutaneous bilirubinometry.新生儿经皮胆红素测定法。
Clin Perinatol. 1985 Feb;12(1):51-62.
8
The measurement of bilirubin fractions in serum.血清中胆红素组分的测定。
Crit Rev Clin Lab Sci. 1991;28(5-6):415-45. doi: 10.3109/10408369109106872.
9
[A new method for the determination of conjugated bilirubin in amniotic fluid].
Geburtshilfe Frauenheilkd. 1970 Nov;30(11):997-1005.
10
Properties and determination of serum and bilirubin.血清及胆红素的性质与测定
Crit Rev Clin Lab Sci. 1984;19(4):267-96. doi: 10.3109/10408368409165765.

引用本文的文献

1
Point-of-Care Capillary Compared to Venous Bilirubin Measurement in Neonates.新生儿即时护理毛细血管胆红素测量与静脉胆红素测量的比较
Indian J Clin Biochem. 2025 Jul;40(3):488-495. doi: 10.1007/s12291-024-01194-z. Epub 2024 Mar 10.
2
Fluorescent protein-based detection of unconjugated bilirubin in newborn serum.基于荧光蛋白的新生儿血清中未结合胆红素检测
Sci Rep. 2016 Jun 21;6:28489. doi: 10.1038/srep28489.