Slepova O S, Murav'eva T V, Zaĭtseva N S
Vopr Virusol. 1978 Jul-Aug(4):452-8.
The dynamics of leukocyte migration inhibition test (LMIT) and blast-transformation (BT) with herpes antigen were studied in 132 patients with ophthalmoherpes, 40 patients with obscure etiology of the eye disease and 40 normal donors. The specific response in LMTT was manifested by both inhibition and stimulation of leukocyte migration. Specific inhibition of leukocyte migration is detected mostly in exacerbations of the clinical process and may serve as a diagnostic sign of activation of herpetic infection in the patient. The specific blast-transformation in the group of patients with ophthalmoherpes was much higher by the rate and level if reaction than in control groups. The maximum level of BTT (up to 25%) was demonstrated in the favourable course of the disease; in severe processes the level was low (up to 2.7%) or the capacity of blast formation was lacking. The test may be prognostic in herpes infections of the eyes.
对132例眼部疱疹患者、40例病因不明的眼病患者及40例正常供者进行了白细胞迁移抑制试验（LMIT）和疱疹抗原激发转化试验（BT）的动力学研究。白细胞迁移抑制试验（LMTT）中的特异性反应表现为白细胞迁移的抑制和刺激。白细胞迁移的特异性抑制主要在临床过程加重时检测到，可作为患者疱疹感染激活的诊断标志。眼部疱疹患者组的特异性激发转化在反应速率和水平上均明显高于对照组。在疾病的有利病程中，BTT达到最高水平（高达25%）；在严重病程中，该水平较低（高达2.7%）或缺乏激发形成能力。该试验对眼部疱疹感染可能具有预后价值。
