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[单纯疱疹病毒抗原对眼部疱疹患者淋巴细胞形成E玫瑰花结的影响]

[Effect of the herpes simplex virus antigen on E rosette formation by the lymphocytes of patients with ocular herpes].

作者信息

Maĭchuk Iu F, Mikuli S G

出版信息

Vopr Virusol. 1985 Jan-Feb;30(1):78-80.

PMID:2986358
Abstract

Herpes simplex virus antigen was demonstrated to inhibit E-rosette formation in most cases of herpetic eye infection in contrast to those of adenovirus eye infection or healthy donors in whom inhibition of spontaneous E-rosette formation in the presence of herpes virus antigen is observed much more rarely. It is suggested that inhibition of E-rosette formation is associated with specific sensitivity of lymphocytes of the subjects under study to herpes antigen. It is also suggested that spontaneous E-rosette formation may be used to determine the degree of T-lymphocyte response to herpes virus antigen.

摘要

与腺病毒眼部感染或健康供体相比,单纯疱疹病毒抗原在大多数疱疹性眼部感染病例中被证实可抑制E玫瑰花结形成,在这些病例中,在疱疹病毒抗原存在下,自发E玫瑰花结形成受到抑制的情况则罕见得多。有人认为,E玫瑰花结形成的抑制与被研究对象的淋巴细胞对疱疹抗原的特异性敏感性有关。也有人认为,自发E玫瑰花结形成可用于确定T淋巴细胞对疱疹病毒抗原的反应程度。

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