Chander R, Kapoort N K
Division of Biochemistry, Central Drug Research Institute, Lucknow, India.
Indian J Exp Biol. 1990 Feb;28(2):195-7.
P. berghei infection in M. natalensis caused a significant reduction in the hepatic SOD and catalase activities. Cu-Zn SOD was more susceptible to infection than Mn SOD. The inhibition of enzyme activities was associated with marked increase in the levels of lipid peroxides, lipid hydroperoxides and conjugated dienes in infected M. natalensis. The alterations in the hepatic SOD, catalase and lipid peroxides are related with the severity of infection.
纳塔尔多乳鼠感染伯氏疟原虫导致肝脏超氧化物歧化酶（SOD）和过氧化氢酶活性显著降低。铜锌超氧化物歧化酶比锰超氧化物歧化酶更易受到感染影响。酶活性的抑制与感染的纳塔尔多乳鼠中脂质过氧化物、氢过氧化物和共轭二烯水平的显著升高有关。肝脏超氧化物歧化酶、过氧化氢酶和脂质过氧化物的变化与感染的严重程度相关。
