Center for Biomedical Engineering Research, University of Delaware, Newark, DE 19716, USA.
Gait Posture. 2012 Jan;35(1):6-10. doi: 10.1016/j.gaitpost.2011.07.012. Epub 2011 Oct 1.
Knee osteoarthritis (OA) is a disease that affects millions of people. While numerous gait differences have been identified between healthy adults and adults with knee OA under normal and challenging conditions, adults with knee OA have not been studied during a challenging weighted walking task. Investigation of the effect of weighted walking on the initial contact and loading response phases of gait was undertaken in 20 healthy and 20 knee OA subjects ages 40-85 years old walking at 1.0m/s while unweighted and weighted with 1/6th of their body weight in a weight vest. Subjects were grouped according to their Kellgren and Lawrence radiographic score and healthy subjects were age-matched to those with knee OA. ANOVA revealed significant effects for hip flexion angle at initial contact, step length, initial double support percent, and load rate. Post hoc t-tests revealed that subjects with knee OA had a larger initial double support percent and hip flexion angle at initial contact and a decreased load rate compared to unweighted, healthy adults. Also, both groups increased their initial double support percent in response to the challenging weighted walking task, but only the healthy adults increased their hip flexion angle at initial contact and decreased their load rate. During the weighted condition, the knee OA group had a shorter step length compared to the healthy group. Because the knee OA group only made minor compensations to their gait strategy, it appears that they may be unable or prefer not to adjust their gait mechanics due to underlying issues.
膝骨关节炎(OA)是一种影响数百万人的疾病。虽然在正常和挑战条件下已经确定了健康成年人和膝骨关节炎成年人之间的许多步态差异,但尚未在挑战性负重行走任务中研究膝骨关节炎成年人。在一项研究中,研究了负重行走对初始接触和负重行走步态的负重响应阶段的影响,该研究纳入了 20 名健康成年人和 20 名年龄在 40-85 岁的膝骨关节炎成年人,他们以 1.0m/s 的速度行走,同时穿着背心负重 1/6 的体重。根据他们的 Kellgren 和 Lawrence 放射评分,将受试者分为两组,健康受试者与膝骨关节炎患者年龄匹配。方差分析显示,初始接触时髋关节屈曲角度、步长、初始双支撑百分比和负荷率存在显著影响。事后 t 检验显示,与未负重的健康成年人相比,膝骨关节炎患者的初始双支撑百分比和初始接触时髋关节屈曲角度更大,负荷率更低。此外,两组在进行挑战性负重行走任务时都增加了初始双支撑百分比,但只有健康成年人增加了初始接触时的髋关节屈曲角度并降低了负荷率。在负重状态下,膝骨关节炎组的步长比健康组短。由于膝骨关节炎组仅对其步态策略进行了轻微的补偿,因此由于潜在问题,他们可能无法或不愿意调整其步态力学。