Anses, agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail, Laboratoire de Sécurité des Aliments de Maisons-Alfort, 23, Avenue du Général de Gaulle, F-94706 Maisons-Alfort, France.
Talanta. 2011 Oct 15;85(5):2605-13. doi: 10.1016/j.talanta.2011.08.027. Epub 2011 Aug 19.
A strategy for the accurate determination in foodstuffs of seven elements liable to be interfered with (V, Cr, Fe, Co, Ni, As and Se), was successfully applied. Firstly, to reduce spectroscopic interferences, four influential factors (hexapole and quadrupole bias, helium and hydrogen flows) of the collision/reaction cell device were optimised through the experimental design methodology. Secondly, non-spectroscopic interferences, which may severely disturb the analysis of matrices containing large amounts of non-target elements, were significantly reduced by a limited decrease in the flow rate of the optimum initial nebuliser rather than with a specific time-consuming dilution. Finally, the optimised multi-element method was subjected to a full validation that demonstrated its acceptable analytical performance.
一种用于准确测定易受干扰元素（V、Cr、Fe、Co、Ni、As 和 Se）的策略已成功应用于食品分析。首先，通过实验设计方法优化了碰撞/反应池装置的四个有影响的因素（六极和四极偏压、氦气和氢气流量），以减少光谱干扰。其次，通过有限地降低最佳初始雾化器的流速，而不是采用特定的耗时稀释方法，显著减少了大量非目标元素基体中可能严重干扰分析的非光谱干扰。最后，对优化后的多元素方法进行了全面验证，证明其具有可接受的分析性能。
