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基于证据的先天性巨细胞病毒检测和治疗管理指南。

Evidence based management guidelines for the detection and treatment of congenital CMV.

机构信息

Paediatric Infectious Diseases Unit, St George's University of London, Cranmer Terrace, London, United Kingdom.

出版信息

Early Hum Dev. 2011 Nov;87(11):723-8. doi: 10.1016/j.earlhumdev.2011.08.021. Epub 2011 Sep 29.

DOI:10.1016/j.earlhumdev.2011.08.021
PMID:21962770
Abstract

CMV is the most common congenital infection in newborns worldwide. Congenital CMV causes sensorineural hearing loss in a significant proportion of infected newborns, while the majority of newborns are asymptomatic. In the last three years there have been significant advances in the diagnosis and treatment of congenital CMV. We have developed practical evidence based guidelines for the management of congenital CMV.

摘要

CMV 是全球新生儿中最常见的先天性感染。先天性 CMV 可导致相当一部分感染新生儿出现感觉神经性听力损失，而大多数新生儿则无症状。在过去三年中，先天性 CMV 的诊断和治疗取得了重大进展。我们已经制定了实用的基于循证的先天性 CMV 管理指南。

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Evidence based management guidelines for the detection and treatment of congenital CMV.基于证据的先天性巨细胞病毒检测和治疗管理指南。
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2
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Oral Valganciclovir treatment in a CMV congenital infected infant with sensorineural hearing loss (SNHL) first detected at 4 months of age.口服缬更昔洛韦治疗一名先天性巨细胞病毒感染婴儿，该婴儿在4个月大时首次被检测出患有感音神经性听力损失（SNHL）。
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Eur J Pediatr. 2025 May 31;184(6):381. doi: 10.1007/s00431-025-06215-4.
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Dosing, Toxicity and Drug Concentrations for Ganciclovir/Valganciclovir in Preterm and Low Birthweight Infants Treated for Cytomegalovirus.巨细胞病毒感染的早产和低出生体重婴儿接受更昔洛韦/缬更昔洛韦治疗的剂量、毒性和药物浓度
Pediatr Infect Dis J. 2025 Apr 1;44(4):319-325. doi: 10.1097/INF.0000000000004605. Epub 2024 Nov 13.
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CMV-induced Hearing Loss.
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Congenit Anom (Kyoto). 2022 Nov;62(6):248-253. doi: 10.1111/cga.12488. Epub 2022 Aug 16.
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Int J Neonatal Screen. 2021 Nov 19;7(4):80. doi: 10.3390/ijns7040080.
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Congenital Human Cytomegalovirus Infection Inducing Sensorineural Hearing Loss.先天性人类巨细胞病毒感染导致感音神经性听力损失。
Front Microbiol. 2021 Apr 14;12:649690. doi: 10.3389/fmicb.2021.649690. eCollection 2021.
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J Int Adv Otol. 2020 Apr;16(1):130-133. doi: 10.5152/iao.2020.6574.
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Vaccines (Basel). 2020 Jan 20;8(1):35. doi: 10.3390/vaccines8010035.
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