犬和人类的角层下脓疱性皮肤病：比较研究

Subcorneal pustular dermatosis in dogs and in human beings: comparative aspects.

作者信息

Kalaher K M, Scott D W

机构信息

Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.

出版信息

J Am Acad Dermatol. 1990 Jun;22(6 Pt 1):1023-8. doi: 10.1016/0190-9622(90)70145-8.

DOI:10.1016/0190-9622(90)70145-8

PMID:2196287

Abstract

Subcorneal pustular dermatosis is a rare disorder in dogs and in human beings. A retrospective study of 13 cases of canine subcorneal pustular dermatosis indicates that many of the clinicopathologic features of this disease are similar in both species. In both the condition is characterized by a variably pruritic, sterile, pustular eruption that is resistant to antibiotics and glucocorticoids. The therapeutic response to dapsone is not uniformly successful in either species, and the disorder tends to be chronic and recurrent.

摘要

角层下脓疱性皮肤病在犬类和人类中都是一种罕见的疾病。一项对13例犬角层下脓疱性皮肤病的回顾性研究表明，该疾病的许多临床病理特征在两个物种中相似。在这两个物种中，该病的特征均为伴有不同程度瘙痒的无菌性脓疱疹，对抗生素和糖皮质激素耐药。氨苯砜的治疗反应在两个物种中均并非一致成功，且该疾病往往呈慢性和复发性。