Boneva-Asiova Zhivka, Boyanov Mihail
Endocrinology Unit, Ministry of the Interior-Medical Institute, Sofia, Bulgaria.
Endocrinol Nutr. 2011 Nov;58(9):472-7. doi: 10.1016/j.endonu.2011.07.004. Epub 2011 Oct 2.
Only scarce information is available on body composition changes with age measured simultaneously by electrical impedance and computed tomography.
We aimed to describe the age-related changes of the body composition and adipose tissue distribution in Bulgarians.
This cross-sectional study included 130 participants (mean age 53±9.8 years, range 35-65), divided according to their body mass index (BMI): BMI <25.0 kg/m(2) (18 women, 12 men); BMI 25.0-34.9 kg/m(2) (50 women, 50 men). Body composition was assessed by bioelectrical impedance on a Tanita TBF-215 analyzer (Tanita Corp., Tokyo, Japan). The abdominal fat was measured by computed tomography on a CT/L scanner (GE Medical Systems, USA).
Increasing age was associated with a mean decrease in body weight by 268 g per year in the normal weight subjects and by 390 g in the overweight ones as well as with a fat-free mass decrease of 321 g and of 291 g per year respectively (p<0.001). One year of increasing age was associated with a mean increase of visceral adipose tissue by 2.43 cm(2) in the overweight group and by 2.68 cm(2) in the normal weight subjects and with a decrease of the subcutaneous adipose tissue by 2.30 cm(2) per year in the latter group (p<0.001). The association of fat mass and fat-free mass with age in men and women was best described by quadratic equations (both increased until the age of 45-50 and decreased thereafter).
Our data showed a significant association between age and decreasing fat-free mass, increasing fat mass and abdominal fat accumulation.
关于通过电阻抗和计算机断层扫描同时测量的身体成分随年龄变化的信息非常有限。
我们旨在描述保加利亚人的身体成分和脂肪组织分布与年龄相关的变化。
这项横断面研究纳入了130名参与者（平均年龄53±9.8岁，范围35 - 65岁），根据体重指数（BMI）进行分组：BMI<25.0 kg/m²（18名女性，12名男性）；BMI 25.0 - 34.9 kg/m²（50名女性，50名男性）。使用Tanita TBF - 215分析仪（日本东京Tanita公司）通过生物电阻抗评估身体成分。使用美国GE医疗系统公司的CT/L扫描仪通过计算机断层扫描测量腹部脂肪。
在正常体重受试者中，年龄增长与体重平均每年下降268克相关，在超重受试者中与体重平均每年下降390克相关，同时分别与无脂肪量每年下降321克和291克相关（p<0.001）。年龄每增加一岁，超重组内脏脂肪组织平均增加2.43 cm²，正常体重受试者平均增加2.68 cm²，且后者皮下脂肪组织每年减少2.30 cm²（p<0.001）。男性和女性的脂肪量和无脂肪量与年龄的关系用二次方程描述最佳（两者在45 - 50岁之前增加，之后减少）。
我们的数据显示年龄与无脂肪量减少、脂肪量增加和腹部脂肪堆积之间存在显著关联。
