Humboldt-Universität zu Berlin, Department of Biology, Laboratory of Freshwater & Stress Ecology, Späthstrasse 80/81, D-12437 Berlin, Germany.
Aquat Toxicol. 2011 Oct;105(3-4):640-2. doi: 10.1016/j.aquatox.2011.08.025. Epub 2011 Sep 8.
DNA-methylation is one pathway of epigenetic programming of gene expression and can be responsive to environmental challenges such as methylating agents in the food. Here we report on the DNA-methylation in the cladocerans Daphnia magna and Moina macrocopa exposed to humic substances, ubiquitous biogeochemicals. The methylation of DNA can alter the stress response, presumably including exposure to synthetic xenobiotic chemicals.
DNA 甲基化是基因表达的表观遗传编程途径之一，可能会对环境挑战做出反应，例如食物中的甲基化剂。在这里，我们报告了在暴露于腐殖质（无处不在的生物地球化学物质）的大型溞（Daphnia magna）和大型溞（Moina macrocopa）中 DNA 的甲基化情况。DNA 的甲基化可以改变应激反应，可能包括暴露于合成的外来化学物质。
