一种通过电化学方法合成吩恶嗪和二吩恶嗪衍生物的新途径。

A new way for synthesis of phenoxazine and diphenoxazine derivatives via electrochemical method.

作者信息

Hosseiny Davarani Saied Saeed, Kalate Bojdi Majid, Mehdinia Ali

机构信息

Department of Chemistry, Faculty of Sciences, Shahid Beheshti University, Tehran, Iran.

出版信息

Chem Pharm Bull (Tokyo). 2011;59(10):1209-13. doi: 10.1248/cpb.59.1209.

DOI:10.1248/cpb.59.1209

PMID:21963628

Abstract

Electrochemical oxidation of hydroquinone (1a) and 2,3-dimethylhydroquinone (1b) have been studied in the presence of 2-aminophenol (3a) and 2-amino-4-chlorophenol (3b), as nucleophiles in phosphate buffer solution (pH 7.2) using cyclic voltammetry and controlled potential coulometry. We proposed different mechanisms for the electrode process. The products were derived with good yield and purity using controlled-potential electrochemical oxidation of 1a, b in the presence of 3a and 3b at the graphite electrode in an undivided cell.

摘要

在磷酸盐缓冲溶液（pH 7.2）中，以2-氨基酚（3a）和2-氨基-4-氯苯酚（3b）作为亲核试剂，采用循环伏安法和控制电位库仑法研究了对苯二酚（1a）和2,3-二甲基对苯二酚（1b）的电化学氧化。我们提出了不同的电极过程机理。在未分隔的电解池中，于石墨电极上，在3a和3b存在的情况下，通过对1a、1b进行控制电位电化学氧化，以良好的产率和纯度获得了产物。