Jung Jung Hwa, Hahm Jong Ryeal, Jung Tae Sik, Kim Hee Jin, Kim Ho Soo, Kim Sungsu, Kim Soo Kyoung, Lee Sang Min, Kim Deok Ryong, Choi Won Jun, Seo Yeong Mi, Chung Soon Il
Department of Internal Medicine, Gyeongsang National University School of Medicine, South Korea.
Intern Med. 2011;50(19):2185-9. doi: 10.2169/internalmedicine.50.5475. Epub 2011 Oct 1.
Polycystic ovary syndrome (PCOS) and Graves' disease are the common causes of menstrual irregularity leading to infertility in women of child-bearing age. A 21-year-old female patient visited us with complaints of oligomenorrhea and hand tremor. She was diagnosed as having PCOS and hyperthyroid Graves' disease, simultaneously. She had low body weight (BMI: 16.4 kg/m(2)), mild hirsutism, and thyrotoxicosis. The patient was treated with anti-thyroid drug and beta-blocker for about two years, and then recovered to normal thyroid function. Although some studies have suggested a connection between PCOS and autoimmune thyroiditis, no study indicated that PCOS is associated with Graves' disease until now. Here, we describe the first case report of a lean woman with normal insulin sensitivity presenting PCOS and Graves' disease simultaneously.
多囊卵巢综合征（PCOS）和格雷夫斯病是育龄女性月经不规律导致不孕的常见原因。一名21岁女性患者因月经过少和手部震颤前来就诊。她被同时诊断为患有PCOS和甲状腺功能亢进性格雷夫斯病。她体重偏低（体重指数：16.4kg/m²），有轻度多毛症和甲状腺毒症。该患者接受抗甲状腺药物和β受体阻滞剂治疗约两年，随后甲状腺功能恢复正常。尽管一些研究表明PCOS与自身免疫性甲状腺炎之间存在联系，但到目前为止，尚无研究表明PCOS与格雷夫斯病有关。在此，我们报告首例同时患有PCOS和格雷夫斯病的瘦型女性病例，其胰岛素敏感性正常。
