Vasileva V A, Ivanov M T, Rumel N B, D'Yachenko A G, Kakubava V V, Danelyan G A
Acta Biol Med Ger. 1978;37(8):1281-7.
The etiology of a disease in rhesus monkeys the main clinical manifestation of which was acute conjunctivitis of an epizootic character has been studied. The cytopathogenic agent well propagating in primarily trypsinized kidney cells of monkeys has been isolated when investigating the affected eye mucosa. It was not pathogenic for laboratory animals. The mean diameter of the virions is 75 nm, the buoyant density in CsCl is 1.34 g/cm3, the viral DNA density is 1.706 g/cm3. The biological properties and findings of physicochemical, electron-microscopic, and serologic investigations allow one to allocate the isolated agent to the SV-37 strain, a representative of the adenovirus group.
对恒河猴中一种疾病的病因进行了研究，该病的主要临床表现为具有 epizootic 特征的急性结膜炎。在调查受影响的眼黏膜时，分离出了一种在经胰蛋白酶初步处理的猴肾细胞中能良好繁殖的细胞致病因子。它对实验动物无致病性。病毒粒子的平均直径为75纳米，在 CsCl 中的浮力密度为1.34克/立方厘米，病毒 DNA 密度为1.706克/立方厘米。生物学特性以及物理化学、电子显微镜和血清学研究结果使人们能够将分离出的因子归为腺病毒组的代表 SV - 37 株。
