Zhang Xi-an, Qi Song-tao, Huang Guang-long, Long Hao, Fan Jun, Peng Jun-xiang
Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.
Childs Nerv Syst. 2012 Jan;28(1):65-72. doi: 10.1007/s00381-011-1599-2. Epub 2011 Oct 2.
In previous studies, some disagreements regarding the nature (inner or outer arachnoid membrane) and lateral boundaries (temporal uncus or tentorial edge) of Liliequist's membrane remain. The aim was to clarify whether Liliequist's membrane is an inner or outer arachnoid membrane, and the distribution of Liliequist's membrane with emphasis on its lateral attachments.
Liliequist's membrane was investigated by microsurgical dissection in 24 formalin-fixed adult cadaver heads and by histological sections of sellar-suprasellar specimens from another four formalin-fixed adult cadaver heads.
The results obtained in the present study indicated that 1) Liliequist's membrane arises from the basal arachnoid membrane and has two components: a basal part comprising a folding inner layer of the arachnoid mater and an attaching part consisting of accumulated arachnoid trabeculae; 2) similar histological features are also present in other inner arachnoid membranes with attachments on basal arachnoid membrane, demonstrating Liliequist's membrane is an inner arachnoid membrane; 3) laterally, Liliequist's membrane attaches to the anterior tentorial edge constantly and to the mesial temporal uncus in more than half; 4) the oculomotor nerve courses above Liliequist's membrane and is fixed on Liliequist's membrane by the oculomotor membrane, which can also attach on temporal uncus and should be differentiated from the true temporal attachments of Liliequist's membrane.
Liliequist's membrane is an inner rather than outer arachnoid membrane. Understanding of its individual variation and topographic relationships with surrounding neurovascular and arachnoid structures is important for neurosurgical practice.
在以往的研究中，关于Liliequist膜的性质（蛛网膜内层或外层）和外侧边界（颞叶钩回或小脑幕边缘）仍存在一些分歧。本研究旨在明确Liliequist膜是蛛网膜内层还是外层，并着重研究其外侧附着情况以阐明Liliequist膜的分布。
通过对24个福尔马林固定的成人尸体头部进行显微外科解剖以及对另外4个福尔马林固定的成人尸体头部的鞍区 - 鞍上标本进行组织学切片，对Liliequist膜进行研究。
本研究结果表明：1）Liliequist膜起源于基底蛛网膜，有两个组成部分：一个基底部分，由蛛网膜内层的折叠构成；一个附着部分，由聚集的蛛网膜小梁组成；2）在其他附着于基底蛛网膜的蛛网膜内层中也存在类似的组织学特征，表明Liliequist膜是蛛网膜内层；3）在外侧，Liliequist膜始终附着于小脑幕前缘，超过半数附着于颞叶内侧钩回；4）动眼神经走行于Liliequist膜上方，并通过动眼神经膜固定于Liliequist膜，动眼神经膜也可附着于颞叶钩回，应与Liliequist膜真正的颞叶附着区分开来。
Liliequist膜是蛛网膜内层而非外层。了解其个体变异以及与周围神经血管和蛛网膜结构的局部关系对神经外科手术实践具有重要意义。
