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蔗糖与行为不良:口服蔗糖耐量试验及营养评估

Sucrose and delinquency: oral sucrose tolerance test and nutritional assessment.

作者信息

Gans D A, Harper A E, Bachorowski J A, Newman J P, Shrago E S, Taylor S L

机构信息

Department of Nutritional Sciences, University of Wisconsin, Madison.

出版信息

Pediatrics. 1990 Aug;86(2):254-62.

PMID:2196523
Abstract

Claims that juvenile delinquency may be associated with reactive hypoglycemia or nutritional deficiencies have received widespread attention but little objective evaluation. To assess the validity of these claims, nutritional and psychological indices of juvenile delinquents have been measured. Serum glucose and insulin profiles during an oral sucrose tolerance test were measured in 137 delinquent and 41 nondelinquent male adolescents aged 14 to 19. In addition, nutritional status of both populations was assessed by anthropometry (height, weight, arm circumference, triceps skin fold) and biochemical measures (hematocrit, red-blood cell thiamin, and serum copper, ferritin, and zinc). Delinquent subjects had slightly but significantly lower serum glucose values at four of six time points (fasting, 60 minutes, 120 minutes, 180 minutes) and higher serum insulin values at one time point (30 minutes) compared with nondelinquent subjects. Changes in glucose from fasting levels indicate that these subjects were regulating serum glucose adequately, but doing so at lower values; changes in insulin from fasting levels indicate that black delinquents initially secreted more insulin than either white subject group. There were no significant associations between excursions in serum glucose or insulin and any adrenergic signs or symptoms of low blood glucose levels. Nutritional status of incarcerated delinquents did not differ from that of nonincarcerated subjects on most measures. Although the significantly lower serum glucose levels and higher serum insulin levels are intriguing, no support is offered by results of this study for allegations that sucrose ingestion causes reactive hypoglycemia in juvenile delinquents or that delinquent male adolescents are at greater risk nutritionally than male adolescents of the same age who are not delinquent.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

青少年犯罪可能与反应性低血糖或营养缺乏有关的说法受到了广泛关注,但客观评估却很少。为了评估这些说法的有效性,已对青少年罪犯的营养和心理指标进行了测量。对137名年龄在14至19岁的犯罪男性青少年和41名非犯罪男性青少年进行了口服蔗糖耐量试验期间的血清葡萄糖和胰岛素水平测定。此外,通过人体测量学(身高、体重、臂围、三头肌皮褶厚度)和生化指标(血细胞比容、红细胞硫胺素、血清铜、铁蛋白和锌)评估了这两组人群的营养状况。与非犯罪青少年相比,犯罪青少年在六个时间点中的四个(空腹、60分钟、120分钟、180分钟)血清葡萄糖值略低但显著较低,在一个时间点(30分钟)血清胰岛素值较高。空腹血糖水平的变化表明这些受试者能够充分调节血清葡萄糖,但调节水平较低;空腹胰岛素水平的变化表明黑人犯罪青少年最初分泌的胰岛素比其他任何一组白人受试者都多。血清葡萄糖或胰岛素的波动与低血糖的任何肾上腺素能体征或症状之间没有显著关联。在大多数测量指标上,被监禁的犯罪青少年的营养状况与未被监禁的受试者没有差异。尽管血清葡萄糖水平显著较低和血清胰岛素水平较高很有趣,但本研究结果并未支持蔗糖摄入会导致青少年罪犯反应性低血糖或犯罪男性青少年比同龄非犯罪男性青少年面临更大营养风险的说法。(摘要截取自250字)

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