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比较腹膜透析和血液透析患者的心脏手术:围手术期结局和两年生存率。

Comparing cardiac surgery in peritoneal dialysis and hemodialysis patients: perioperative outcomes and two-year survival.

机构信息

Southern California Permanente Medical Group, Los Angeles, California, USA.

出版信息

Perit Dial Int. 2012 Mar-Apr;32(2):137-41. doi: 10.3747/pdi.2010.00263. Epub 2011 Sep 30.

Abstract

BACKGROUND

We sought to compare perioperative outcomes and 2-year survival in a cohort of peritoneal dialysis (PD) patients compared with matched hemodialysis (HD) patients who underwent cardiothoracic surgery at our institution.

METHODS

We obtained a list of all dialysis-dependent patients who underwent cardiac surgery (coronary artery bypass grafting, valve replacement, or both) at our center between 1994 and 2008. All patients undergoing PD at the time of surgery were included in our analysis. Two HD patients matched for age, diabetes status, and Charleston comorbidity score were obtained for each PD patient.

RESULTS

The analysis included 36 PD patients and 72 HD patients. Mean age, sex, diabetes status, cardiac unit stay, hospital stay, and operative mortality did not differ by dialysis modality. The incidence of 1 or more postoperative complications (infection, prolonged intubation, death) was higher for HD patients (50% vs. 28% for PD patients, p = 0.046). After surgery, 2 PD patients required conversion to HD. The 2-year survival was 69% for PD patients and 66% for HD patients (p = 0.73).

CONCLUSIONS

Our findings suggest that, compared with HD patients, PD patients who require cardiac surgery do not experience more early complications or a lesser 2-year survival and that 2-year survival for dialysis patients after cardiac surgery is acceptable.

摘要

背景

我们旨在比较在我院接受心胸外科手术的腹膜透析(PD)患者和匹配的血液透析(HD)患者的围手术期结局和 2 年生存率。

方法

我们获取了 1994 年至 2008 年期间在我院接受心脏手术(冠状动脉旁路移植术、瓣膜置换术或两者兼而有之)的所有依赖透析的患者名单。所有在手术时接受 PD 的患者均纳入我们的分析。为每位 PD 患者匹配了年龄、糖尿病状况和Charlson 合并症评分相匹配的 2 名 HD 患者。

结果

该分析纳入了 36 名 PD 患者和 72 名 HD 患者。透析方式之间的平均年龄、性别、糖尿病状况、心脏科住院时间、住院时间和手术死亡率无差异。HD 患者的术后并发症(感染、延长插管、死亡)发生率高于 PD 患者(50% vs. PD 患者的 28%,p = 0.046)。手术后,2 名 PD 患者需要转为 HD。PD 患者的 2 年生存率为 69%,HD 患者的 2 年生存率为 66%(p = 0.73)。

结论

与 HD 患者相比,需要心脏手术的 PD 患者并未经历更多的早期并发症或较低的 2 年生存率,而且透析患者心脏手术后的 2 年生存率是可以接受的。

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