适合作为脂质头部基团的含N，N-二甲基氨基单体的多样文库的合成。
Synthesis of a Diverse Library of N,N-Dimethylamino Containing Monomers Appropriate as Lipid Head Groups.
作者信息
Jones Ian W, Simon Anne M, Saavedra S Scott, Hall H K
机构信息
Department of Biochemistry and Chemistry, University of Arizona, Tucson AZ, 85721.
出版信息
Tetrahedron Lett. 2011 Oct 26;52(43):5547-5549. doi: 10.1016/j.tetlet.2011.08.042.
Abstract
We report on the synthesis of a diverse library of N,N-dimethylamino containing monomers. Subjecting these monomers to Chabrier reaction conditions would yield lipids with polymerizable head groups. This library of lipid head groups is equipped with a variety of arm lengths containing reduction-oxidation polymerizable groups at the terminus.
摘要
我们报道了一系列含N，N - 二甲基氨基单体的合成。使这些单体处于查布里尔反应条件下会生成具有可聚合头部基团的脂质。这个脂质头部基团文库配备了各种不同臂长的结构，其末端含有氧化还原可聚合基团。
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