Hammer A S, Couto C G
Department of Veterinary Clinical Sciences, Ohio State University College of Veterinary Medicine, Columbus.
Vet Clin North Am Small Anim Pract. 1990 Jul;20(4):1015-36. doi: 10.1016/s0195-5616(90)50082-0.
The use of adjuvant chemotherapy appears to offer many advantages to the patient with cancer. However, objective information is difficult to compile. Clinical trials all too often have only a small number of patients. In order to best demonstrate the usefulness of adjuvant chemotherapy, many of the cases discussed here had bulky disease. Based on the known principles of chemotherapy, animals with minimal residual disease following surgery would most likely benefit from adjuvant chemotherapy. By using the principles discussed at the beginning of this article and information from clinical trials, veterinarians will better be able to inform clients of possible benefits and risks in treating their pets with chemotherapy.