Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, Queen Square, London, United Kingdom.
Epilepsia. 2011 Oct;52 Suppl 8:61-3. doi: 10.1111/j.1528-1167.2011.03240.x.
There is a long history of the use of brain stimulation in the treatment of epilepsy but relatively little experience for its use in status epilepticus. Electroconvulsive therapy, transcranial magnetic stimulation, subcortical and cortical stimulation have all been tried with varying degrees of success in single cases or small case series. It remains unclear, however, which brain areas should be stimulated and the parameters that should be used. Moreover, the aim (stopping status epilepticus) is different from preventing seizures and so the brain areas and parameters that are useful in epilepsy may not directly translate to the treatment of status epilepticus.
脑刺激在癫痫治疗中的应用历史悠久,但在癫痫持续状态中的应用经验相对较少。电惊厥疗法、经颅磁刺激、皮质下和皮质刺激在单病例或小病例系列中都取得了不同程度的成功。然而,目前仍不清楚应该刺激哪些脑区以及应该使用哪些参数。此外,目的(停止癫痫持续状态)与预防癫痫发作不同,因此在癫痫治疗中有用的脑区和参数可能不能直接转化为癫痫持续状态的治疗。