化疗后非精原细胞瘤生殖细胞肿瘤残余肿瘤的处理。
Management of residual mass in nonseminomatous germ cell tumors following chemotherapy.
机构信息
USC Institute of Urology, 1441 East Lake Avenue, Suite 7461, Los Angeles, CA 90033, USA.
出版信息
Ther Adv Urol. 2011 Aug;3(4):163-71. doi: 10.1177/1756287211418721.
Abstract
Advanced stage nonseminomatous testis cancer is commonly treated with chemotherapy and surgical resection. Patients with retroperitoneal residual masses >1cm following induction chemotherapy with normalized tumor markers should undergo a post-chemotherapy retroperitoneal lymph node dissection. Post chemotherapy retroperitoneal residual mass less than 1 cm with normal markers may be considered as complete response, although the possibility of residual teratoma and viable germ cell tumor are not definitively ruled out. Excellent long term disease free survival following surveillance may justify this option as the treatment of choice in this cohort of patients.
摘要
晚期非精原细胞瘤性睾丸癌通常采用化疗和手术切除进行治疗。对于化疗后肿瘤标志物正常、腹膜后残留肿块＞1cm 的患者，应进行化疗后腹膜后淋巴结清扫术。对于化疗后腹膜后残留肿块＜1cm 且肿瘤标志物正常的患者，可考虑为完全缓解，但不能排除残留畸胎瘤和有活力的生殖细胞瘤的可能性。在进行监测的情况下，患者长期无疾病生存的效果良好，这一结果可能证明该方案在该患者群体中为首选治疗方法。
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