Jongjirasiri Sutipong, Sritara Chanika, Waeosak Phanloet, Laothamatas Jiraporn
Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 2011 Sep;94(9):1053-60.
Delineate normal data in a Thai population for global left ventricular function, left ventricular mass (LVM), and LV mass index (LVMI) by gated volumetric CT angiography (CTA).
Two hundred twenty seven patients with intermediate risk factors for CAD were referred for CT coronary angiography. The non-hypertensive and non-diabetic asymptomatic group was selected with negative coronary CTA. Pre-condition of mild stenosis or less than 50% area stenosis was consistently met for inclusion in the present study. One hundred fifteen patients were included (31 males, 84 females, age range 38-76 years, mean 54.6 +/- 7.2 for males and 54.0 +/- 6.8 for females respectively).
Mean EDV, ESV, SV, CO, and EF in male and females were EDV 122.6 +/- 17.3 vs. 94.9 +/- 16.6ml, ESV 48.2 +/- 9.9 vs. 34.1 +/- 9.1 ml, SV 74.5 +/- 14.2 vs. 60.8 +/- 10.6 ml, CO 4.2 +/- 0.8vs. 3.6 +/- 0.7 Land EF 60.6 +/- 6.6 vs. 64.3 +/- 5.6% respectively The mean LVM and LVMI were higher in males than females (LVM 134.6 +/- 21.4 vs. 96 9 +/- 20.3 g, and LVMI 76.8 +/- 12.4 vs. 61.1 +/- 11.56 g/m2). Altman and Bland plot for each of them showed that the mean and standard deviation of the differences was constant throughout the range of measurements. Each histogram of differences showed that these differences correspond to approximately normal distribution, indicating that the required assumptions held for the use of 95% limits of agreement are valid.
Data from this group represents healthy volunteers and this may serve as an important source of information representing normal reference values to be used for Thai patients.
通过门控容积CT血管造影（CTA）描绘泰国人群左心室整体功能、左心室质量（LVM）和左心室质量指数（LVMI）的正常数据。
227例有冠心病中度危险因素的患者接受CT冠状动脉造影检查。选择冠状动脉CTA阴性的非高血压、非糖尿病无症状组。纳入本研究的患者均符合轻度狭窄或面积狭窄小于50%的前提条件。共纳入115例患者（男性31例，女性84例，年龄范围38 - 76岁，男性平均年龄54.6±7.2岁，女性平均年龄54.0±6.8岁）。
男性和女性的平均舒张末期容积（EDV）、收缩末期容积（ESV）、每搏输出量（SV）、心输出量（CO）和射血分数（EF）分别为：EDV 122.6±17.3 vs. 94.9±16.6ml，ESV 48.2±9.9 vs. 34.1±9.1ml，SV 74.5±14.2 vs. 60.8±10.6ml，CO 4.2±0.8 vs. 3.6±0.7L，EF 60.6±6.6 vs. 64.3±5.6%。男性LVM和LVMI的平均值高于女性（LVM 134.6±21.4 vs. 96.9±20.3g，LVMI 76.8±12.4 vs. 61.1±11.56g/m²）。对上述各项指标进行的Altman和Bland分析表明，在整个测量范围内，差异的均值和标准差是恒定的。差异的每个直方图显示，这些差异近似正态分布，表明使用95%一致性界限所需的假设是有效的。
该组数据代表健康志愿者，可作为泰国患者正常参考值的重要信息来源。
