Department of Medicine, Brigham and Women's Hospital, Boston, MA 02120, USA.
J Hosp Med. 2012 Feb;7(2):104-9. doi: 10.1002/jhm.948. Epub 2011 Oct 3.
The affordability of prescription medications continues to be a major public health issue in the United States. Estimates of cost-related medication underuse come largely from surveys of ambulatory patients. Hospitalized patients may be vulnerable to cost-related underuse and its consequences, but have been subject to little investigation.
To determine impact of medication costs in a cohort of hospitalized managed care beneficiaries.
We surveyed consecutive patients admitted to medical services at an academic medical center. Questions about cost-related underuse were based on validated measures; predictors were assessed with multivariable models. Participants were asked about strategies to improve medication affordability, and were contacted after discharge to determine if they had filled newly prescribed medications.
One-hundred thirty (41%) of 316 potentially eligible patients participated; 93 (75%) of these completed postdischarge surveys. Thirty patients (23%) reported cost-related underuse in the year prior to admission. In adjusted analyses, patients of black race were 3.39 times (95% confidence interval [CI], 1.05 to 11.02) more likely to report cost-related underuse than non-Hispanic white patients. Virtually all respondents (n = 123; 95%) endorsed at least 1 strategy to make medications more affordable. Few (16%) patients, prescribed medications at discharge, knew how much they would pay at the pharmacy. Almost none had spoken to their inpatient (4%) or outpatient (2%) providers about the cost of newly prescribed drugs.
Cost-related underuse is common among hospitalized patients. Individuals of black race appear to be particularly at risk. Strategies should be developed to address this issue around the time of hospital discharge.
在美国,处方药的负担能力仍是一个主要的公共卫生问题。关于与费用相关的药物使用不足的估计主要来自对门诊患者的调查。住院患者可能容易受到与费用相关的药物使用不足及其后果的影响,但对此研究甚少。
在一组住院管理式医疗受益人群中确定药物费用的影响。
我们调查了在学术医疗中心接受医疗服务的连续住院患者。与费用相关的药物使用不足问题的调查依据是经过验证的措施;采用多变量模型评估预测因素。询问患者改善药物可负担性的策略,并在出院后联系他们,以确定他们是否已开出新处方的药物。
在 316 名可能符合条件的患者中,有 130 名(41%)参与了调查;其中 93 名(75%)完成了出院后的调查。在入院前的一年中,有 30 名(23%)患者报告存在与费用相关的药物使用不足。在调整后的分析中,黑种人患者报告与费用相关的药物使用不足的可能性是未报告该问题的非西班牙裔白人患者的 3.39 倍(95%置信区间[CI],1.05 至 11.02)。几乎所有(n = 123;95%)的受访者都认可至少 1 种使药物更负担得起的策略。很少(16%)的患者在出院时开了处方,知道在药店需要支付多少费用。几乎没有人向他们的住院(4%)或门诊(2%)医生询问新处方药物的费用。
与费用相关的药物使用不足在住院患者中很常见。黑种人似乎尤其处于风险之中。应该在出院时制定解决这一问题的策略。