一种与β2-微球蛋白相关的禽类B淋巴细胞蛋白。
An avian B-lymphocyte protein associated with beta 2-microglobulin.
作者信息
Pickel J M, Chen C L, Cooper M D
机构信息
Department of Pediatrics, University of Alabama, Birmingham 35294.
出版信息
Immunogenetics. 1990;32(1):1-7. doi: 10.1007/BF01787321.
A member of the family of beta 2-microglobulin (beta 2m)-associated cell surface glycoproteins was identified by the CB3 monoclonal antibody. The Mr 50,000 heavy chain of the CB3 antigen differs from conventional class I heavy chains (Mr 45,000) in the extent of glycosylation, charge, and peptide composition. Because of its selective expression on avian B cells and its similarity to mammalian class I-like molecules, we speculate that the CB3 antigen may play a role in T- and B-cell interactions,
通过CB3单克隆抗体鉴定出一种与β2-微球蛋白（β2m）相关的细胞表面糖蛋白家族成员。CB3抗原的50,000道尔顿重链在糖基化程度、电荷和肽组成方面与传统的I类重链（45,000道尔顿）不同。由于其在禽类B细胞上的选择性表达以及与哺乳动物I类样分子的相似性，我们推测CB3抗原可能在T细胞和B细胞相互作用中发挥作用。
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