Lou Ruvo Center for Brain Health, Cleveland Clinic, 888 West Bonneville, Las Vegas, NV 89106, USA.
Cleve Clin J Med. 2011 Aug;78 Suppl 1:S44-6. doi: 10.3949/ccjm.78.s1.07.
Depression has been linked to cardiovascular disease and cognitive impairment, including Alzheimer disease, but the exact nature of the relationship is poorly understood. Although depression seems to progress little after the onset of Alzheimer disease, depression in earlier life increases the risk of dementia and cognitive impairment many years in the future. Depression is also associated with reduced vascular function and is a poorly recognized but significant risk factor for stroke.
抑郁症与心血管疾病和认知障碍有关，包括阿尔茨海默病，但两者的确切关系尚不清楚。尽管抑郁症似乎在阿尔茨海默病发病后进展缓慢，但早年的抑郁症会增加未来多年痴呆和认知障碍的风险。抑郁症还与血管功能下降有关，是一个被低估但重要的中风危险因素。
