Department of Pharmacology and Neuroscience, Institute for Aging and Alzheimer's Disease Research, University of North Texas Health Science Center, 3500 Camp Bowie Blvd., Fort Worth, TX 76107, USA.
Cleve Clin J Med. 2011 Aug;78 Suppl 1:S47-9. doi: 10.3949/ccjm.78.s1.08.
To help define the relationships among inflammation, Alzheimer disease, and depression, the Texas Alzheimer's Research Consortium analyzed an array of inflammatory biomarkers in a cohort of patients with Alzheimer disease and in controls. Inflammation severity was highly correlated with earlier age at onset of Alzheimer disease and was also associated with cognitive decline. The relationship between inflammation and depression was not as clear, and it varied with aspects of depression, gender, and the presence of Alzheimer disease.
为了帮助定义炎症、阿尔茨海默病和抑郁症之间的关系，德克萨斯州阿尔茨海默病研究联合会在一组阿尔茨海默病患者和对照组中分析了一系列炎症生物标志物。炎症严重程度与阿尔茨海默病发病年龄较早高度相关，也与认知能力下降有关。炎症与抑郁症之间的关系并不那么明确，而且它因抑郁症的各个方面、性别和阿尔茨海默病的存在而有所不同。
