Ruzicka T, Donhauser G, Linke R P, Landthaler M, Bieber T
Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München.
Hautarzt. 1990 May;41(5):245-55.
Significant advances in basic research in biochemistry and immunology has tremendously increased our understanding of amyloidoses. The chemical structure of several amyloid proteins has been partly characterized. Specific antibodies may provide new methods for immunohistological diagnosis of amyloidoses. Cutaneous manifestations can affect the skin only or develop during the course of systemic amyloidoses. Although these conditions are so rare, dermatologists should be aware of the changing clinical manifestations of cutaneous amyloidoses if they wish to avoid diagnostic failures.
生物化学和免疫学基础研究的重大进展极大地增进了我们对淀粉样变性的理解。几种淀粉样蛋白的化学结构已得到部分表征。特异性抗体可能为淀粉样变性的免疫组织学诊断提供新方法。皮肤表现可能仅累及皮肤，或在系统性淀粉样变性病程中出现。尽管这些病症非常罕见，但皮肤科医生若想避免诊断失误，就应了解皮肤淀粉样变性不断变化的临床表现。
