Naydenov E, Tzekov Chr, Bussarsky V, Nachev S, Tzekova V, Hadjieva T
Khirurgiia (Sofiia). 2010(4-5):36-41.
Glioblastoma multiforme is the most common primary malignant brain tumor in adults. The actual treatment approach includes surgical excision of the lesion followed by radio- and chemotherapy in standard doses and regimens. In most cases, in spite of aggressive treatment, the survival does not exceed 12-16 months after the initial diagnosis. The present survey provides systematic information about the current treatment modalities for control of the disease as well as the perspectives of introduction of some experimental methods in clinical practice.
多形性胶质母细胞瘤是成人中最常见的原发性恶性脑肿瘤。实际治疗方法包括手术切除病灶,随后按标准剂量和方案进行放疗和化疗。在大多数情况下,尽管进行了积极治疗,但初次诊断后的生存期不超过12至16个月。本综述提供了有关当前控制该疾病的治疗方式以及在临床实践中引入一些实验方法的前景的系统信息。