Yaramov N, Sokolov M, Angelov K, Petrov B, Pavlov V
Khirurgiia (Sofiia). 2010(2-3):5-7.
There is approximately 300 cases of malignant melanoma written in the world literature. We write up 13 operated from us for 15 years cases of melanoma of the anus and rectum. The neoplastic localization is usually at linea dentate area. The patients complains are foreign-body filling and rectohaemorrhagy. This formation considers like haemorrhoid frequently. The pain is not common symptom but ulceration occurs in many percent. The metastasing is in the inguinal lymph nodes. The tumor colour is between light-brown to red-purple in 50% of the cases. The colouring matter is absent in the other half of the cases and these tumors consider like nonpigmentous melanoes. Despite the complex treatment--surgical, chemotherapy etc. the prognosis is at large poor.
世界文献中记载了约300例恶性黑色素瘤病例。我们整理了15年间我们收治的13例肛门和直肠黑色素瘤手术病例。肿瘤通常位于齿状线区域。患者的主诉是有异物感和直肠出血。这种病变常被误诊为痔疮。疼痛并非常见症状,但很多病例会出现溃疡。转移至腹股沟淋巴结。50%的病例中肿瘤颜色介于浅棕色至红紫色之间。另一半病例中没有色素沉着,这些肿瘤被视为无色素性黑色素瘤。尽管采取了综合治疗——手术、化疗等,但总体预后很差。