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[HIV感染中的热带疟疾]

[Malaria tropica in HIV infection].

作者信息

Weinke T, Scherer W, Pohle H D

机构信息

Universitätsklinikum Rudolf Virchow, Freie Universität Berlin, II. Medizinische Klinik, Berlin.

出版信息

Klin Wochenschr. 1990 May 17;68(10):533-6. doi: 10.1007/BF01648252.

Abstract

This is a case report of a 24 year-old woman who is HIV-infected since three years (stage III B, CDC). She developed malaria tropica during her touristic stay in the Cameroons, Africa. No clinical complications were detectable even though she had a high parasitemia of 18% blood cells infected with Plasmodium falciparum. After quinine therapy defervescence occurred and blood smears were continuously free of malaria parasites. P. falciparum infection may increase HIV-related immunosuppression which favours the earlier occurrence of AIDS indicative opportunistic infections. Malaria in combination with HIV-infection can lead to a higher parasitemia; this does not necessarily lead to a higher rate of complications.

摘要

这是一例关于一名24岁女性的病例报告,她三年前感染了艾滋病毒(疾病控制与预防中心III B期)。她在非洲喀麦隆旅游期间感染了热带疟疾。尽管她的疟原虫血症很高,有18%的血细胞被恶性疟原虫感染,但未发现临床并发症。经过奎宁治疗后体温下降,血液涂片持续未发现疟原虫。恶性疟原虫感染可能会加重与艾滋病毒相关的免疫抑制,这有利于更早出现艾滋病指征性机会性感染。疟疾与艾滋病毒感染相结合可导致更高的疟原虫血症;但这不一定会导致更高的并发症发生率。

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