Meyer A, Dörlemann A, Dietrich M
Bernhard-Nocht-Institut für Tropenmedizin, Hamburg.
Med Klin (Munich). 1990 Apr;85 Suppl 2:258-9.
In 22 HIV positive patients a mild to moderate pneumocystis carinii pneumonia was treated by daily inhalation for 21 days of 600 mg pentamidine, divided into two inhalation phases with the inhalation of 300 mg pentamidin each. In 13 patients (59%) treatment was successful. In five cases, therapy was stopped in the first treatment week because of lacking clinical effectiveness resp. clinical deterioration. In four cases, therapy was discontinued in the further course. The subsequent treatment was successful in all cases. In the case of otherwise good tolerance, in two cases there was a hypoglycemia, in one case with clinical signs. In no case there was any sign of an extrapulmonary pneumocystosis.
对22例HIV阳性患者的轻至中度卡氏肺孢子虫肺炎进行治疗,每日吸入600毫克喷他脒,共21天,分为两个吸入阶段,每次吸入300毫克喷他脒。13例患者(59%)治疗成功。5例患者在治疗的第一周因缺乏临床疗效或临床病情恶化而停止治疗。4例患者在后续治疗过程中停止治疗。所有病例后续治疗均成功。在耐受性良好的情况下,2例出现低血糖,1例有临床症状。无一例有肺外肺孢子虫病的迹象。