右侧腮腺先天缺失使颅颈神经母细胞瘤的 MIBG 扫描解读变得复杂。

Congenital agenesis of right parotid gland confounds MIBG scan interpretation in craniocervical neuroblastoma.

机构信息

The Russell H Morgan Department of Radiology and Radiological Science, Division of Nuclear Medicine, Johns Hopkins University, Baltimore, MD 95817, USA.

出版信息

Clin Nucl Med. 2011 Nov;36(11):e162-4. doi: 10.1097/RLU.0b013e318219b2b9.

DOI:10.1097/RLU.0b013e318219b2b9

PMID:21975413

Abstract

A 10-month-old boy with left infraorbital temporal neuroblastoma presented for I-123 metaiodobenzylguanidine scan with SPECT/CT for staging. Symmetrical metaiodobenzylguanidine uptake in salivary glands is usually considered normal. In this case of right parotid agenesis, symmetrical uptake was misleading. Tumor in the right mandibular ramus masqueraded as normal parotid gland. Repeat imaging 3 months after chemotherapy revealed absence of physiologic right parotid gland activity. Correlation with CT from SPECT/CT demonstrated right parotid agenesis, confirmed on MRI. Few cases of unilateral parotid agenesis are reported in published literature. We also discuss the potential added value of higher-quality CT images in SPECT/CT tumor imaging.

摘要

一位 10 个月大的男孩，因左侧眶颞神经母细胞瘤就诊，进行 I-123 间碘苄胍 SPECT/CT 扫描以进行分期。唾液腺摄取对称的间碘苄胍通常被认为是正常的。在右腮腺发育不全的情况下，对称摄取具有误导性。右下颌支的肿瘤伪装成正常的腮腺。化疗后 3 个月的重复成像显示，右侧腮腺的生理性活动缺失。与 SPECT/CT 的 CT 进行相关性分析显示，右侧腮腺发育不全，在 MRI 上得到证实。在已发表的文献中，仅报道了少数单侧腮腺发育不全的病例。我们还讨论了 SPECT/CT 肿瘤成像中高质量 CT 图像的潜在附加价值。