淋巴瘤的造血细胞移植。
Hematopoietic cell transplantation for lymphomas.
机构信息
Blood and Marrow Transplant Program, Moffitt Cancer Center, Tampa, FL 33612, USA.
出版信息
Cancer Control. 2011 Oct;18(4):246-57. doi: 10.1177/107327481101800405.
BACKGROUND
The heterogeneity of lymphomas results in numerous treatment options, including both autologous and allogeneic hematopoietic cell transplantation. However, the type of transplantation, the timing the procedure, and the selection of suitable patients for transplant continue to evolve.
METHODS
We reviewed the current medical literature to provide a succinct synthesis for the most common types of lymphoma and the indications for transplantation.
RESULTS
This review discusses the outcomes of autologous and allogeneic transplantation for patients with diffuse large B-cell lymphoma, follicular lymphoma, HIV-associated lymphomas, mantle cell lymphoma, T-cell lymphoma, and Hodgkin lymphoma.
CONCLUSIONS
Each of these histologies differs in the indications and timing for transplantation. However, ongoing clinical trials support the continuing role of both autologous and allogeneic transplantation for lymphoma management.
背景
淋巴瘤的异质性导致了众多治疗选择，包括自体和异基因造血细胞移植。然而，移植类型、手术时机以及选择适合移植的患者仍在不断发展。
方法
我们回顾了当前的医学文献，为最常见的淋巴瘤类型和移植适应证提供了简洁的综合论述。
结果
本综述讨论了自体和异基因移植治疗弥漫性大 B 细胞淋巴瘤、滤泡性淋巴瘤、HIV 相关淋巴瘤、套细胞淋巴瘤、T 细胞淋巴瘤和霍奇金淋巴瘤患者的结果。
结论
这些组织学类型在移植的适应证和时机上有所不同。然而，正在进行的临床试验支持自体和异基因移植在淋巴瘤管理中的持续作用。
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