Pediatric Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA.
J Clin Microbiol. 2011 Dec;49(12):4330-2. doi: 10.1128/JCM.05031-11. Epub 2011 Oct 5.
We demonstrated that sodium gluconate was the factor causing false-positive galactomannan (GM) antigenemia of Plasma-Lyte hydration solution. Infusion of sodium gluconate-containing solution but not gluconate-free Plasma-Lyte resulted in positive serum GM antigenemia. Serum GM concentrations also correlated with the volume and in vitro concentrations of GM within gluconate-containing solutions of infused Plasma-Lyte.
我们证明了葡萄糖酸钠是导致 Plasma-Lyte 补液盐中半乳甘露聚糖(GM)抗原血症假阳性的因素。含有葡萄糖酸钠的溶液输注而不是无葡萄糖酸钠的 Plasma-Lyte 会导致血清 GM 抗原血症阳性。血清 GM 浓度也与输注的含有葡萄糖酸钠的 Plasma-Lyte 溶液中 GM 的体积和体外浓度相关。