Dutta Samrat, Chattopadhayay Subrata, Dasgupta C, Sarkar Shyamal
Department of Radiotherapy, Medical College and Hospital, Kolkata, India.
Indian J Palliat Care. 2011 May;17(2):143-5. doi: 10.4103/0973-1075.84536.
Deep vein thrombosis (DVT) is one of the many cause of pain in advance cases of carcinoma cervix. The most widely used agent for combating DVT is unfractionated heparin.
Aims of this study is to see the efficacy of the use of low molecular weight (LMW) haparin and its practical utility in palliative care settings.
Twelve cases of established DVT received enoxaparin at 40 mg/m with warfarin.
There was 70% resolution of limb swelling in seven cases. Out of remaining four cases took two months to resolve and one case did not resolve completely.
LMV heparin is effective in palliative care setting and also has added advantage of subcutaneous route of administration.
深静脉血栓形成(DVT)是晚期宫颈癌疼痛的众多原因之一。用于对抗DVT最广泛使用的药物是普通肝素。
本研究的目的是观察低分子量(LMW)肝素的使用效果及其在姑息治疗环境中的实际效用。
12例确诊的DVT患者接受了40mg/m的依诺肝素联合华法林治疗。
7例患者肢体肿胀消退了70%。其余4例患者肿胀消退需要两个月,1例患者肿胀未完全消退。
低分子量肝素在姑息治疗环境中有效,并且具有皮下给药的额外优势。