Tendas A, Boschetto C, Baraldi L, Caiazza E, Cupelli L, Lentini R, Trawinska M, Palombi M, Ales M, Morino L, Giovannini M, Scaramucci L, Cartoni C, Dentamaro T, Arcese W, de Fabritiis P, Niscola P, Mandelli F
Hematology Unit, S. Eugenio Hospital, Home Care Service "Giuseppe Papa" of the Rome Section of the Italian Association Against Leukemias, Rome, Italy.
Indian J Palliat Care. 2011 May;17(2):159-61. doi: 10.4103/0973-1075.84540.
Chronic graft versus host disease (cGVHD) is a frequent complication of allogeneic stem cell transplantation. Extensive musculoskeletal and skin involvement may induce severe functional impairment, disability and quality of life deterioration. Physical rehabilitation is recommended as ancillary therapy in these forms, but experiences are sparse. A 39-year-old man affected by musculoskeletal and skin chronic graft versus host disease (cGVHD) was treated with a homecare-based motor rehabilitation program during palliation for disease progression. Significant functional improvement was obtained. Motor rehabilitation should be strongly considered for patients with musculoskeletal cGVHD, both in the palliative and in the curative phase of disease.
慢性移植物抗宿主病(cGVHD)是异基因干细胞移植常见的并发症。广泛的肌肉骨骼和皮肤受累可能导致严重的功能障碍、残疾和生活质量下降。对于这些情况,推荐进行物理康复作为辅助治疗,但相关经验经验却较少。一名39岁患有肌肉骨骼和皮肤慢性移植物抗宿主病(cGVHD)的男性患者,在疾病进展的姑息治疗期间接受了基于家庭护理的运动康复计划,获得了显著的功能改善。对于患有肌肉骨骼cGVHD的患者,无论在疾病的姑息治疗阶段还是治愈阶段,都应强烈考虑进行运动康复。